Biostimulators are injectable treatments designed to encourage the skin’s natural regenerative processes, particularly collagen production. Rather than simply adding volume, they work by stimulating the skin’s own structural support over time, helping improve skin quality, firmness and overall appearance.

Biostimulators work by activating a controlled biological response within the skin. This encourages new collagen formation, which plays an important role in maintaining skin firmness, elasticity and structural integrity. Results develop gradually as the skin’s regenerative processes take place.

Depending on the treatment selected, potential benefits may include:

• Improved skin firmness and elasticity.

• Support for collagen production.

• Improved skin texture and quality.

• Improved appearance of skin laxity.

• Restoration of selected areas of structural support.

• A gradual, natural-looking improvement.

Depending on the formulation and individual suitability, treatment may be considered for areas including the cheeks, temples, jawline, neck, under eye, décolletage, upper arms, abdomen, thighs and buttocks.

Not every biostimulator is suitable for every area.

Certain specialised formulations may be suitable for the delicate under-eye region, where concerns can include fine lines, crepey skin and changes in skin quality. Depending on the formulation, treatments may support hydration, improve the appearance of the skin and stimulate collagen production over time. Suitability depends on individual anatomy, skin thickness and the cause of the concern. 

Traditional volume treatments are primarily used to provide immediate volume, contour or structural support. Biostimulators are designed to encourage the body’s own collagen production, with improvements developing progressively over time.

Some injectable treatments may have overlapping characteristics, so treatment selection depends on the desired outcome and individual anatomy.

Unlike treatments that provide immediate volume, biostimulator results generally develop gradually. Initial changes may become noticeable over several weeks, with further improvements occurring over the following months as collagen production develops.

The timeframe varies according to the treatment, formulation and individual response.

Biostimulator treatments are designed to encourage the body’s natural collagen production, helping improve skin firmness, elasticity and structural support over time.

Results can last anywhere from approximately 12 months to 2 years or longer, depending on the treatment formulation, treatment area, amount used, individual collagen response and ageing process.

Although the initial treatment material is gradually metabolised or broken down, the collagen produced in response may remain for longer. However, collagen continues to age and remodel naturally, so results are not permanent.

Factors influencing longevity include:

• Treatment formulation: Different biostimulators have different mechanisms of action and longevity profiles.

• Treatment area: Facial skin, neck, décolletage and body areas can respond differently.

• Individual collagen response: Age, genetics, skin condition and metabolic factors influence results.

• Lifestyle: Sun exposure, smoking, nutrition and general health can affect collagen maintenance.

• Treatment protocol: The number of sessions, treatment intervals and initial treatment plan can influence outcomes.

In some cases, biostimulators may form part of a broader skin rejuvenation plan alongside treatments such as skin needling, energy-based skin tightening or skin-quality treatments. The combination and timing depend on individual suitability and clinical assessment.

At Celluderm Skin Aesthetics, we take a personalised approach to treatment selection. Your consultation will assess your skin quality, structural support, areas of concern and desired outcomes to determine the most appropriate treatment approach.

Not necessarily. Suitability depends on your medical history, skin condition, anatomy, treatment goals and the specific injectable formulation. A consultation is essential to determine whether a biostimulator is appropriate for you.